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Theres evidence suggesting there may be potential slight worsening of diabetic retinopathy with semaglutide, a 2023 study found

2012 Jul 31;2(3):203a10

Should it still be the first-line agent, or have newer drug classes like GLP1 receptor agonists and SGLT2 inhibitors earned that spot

Rifaximin enhances the Lcarnitinemediated preventive effects on skeletal muscle atrophy in cirrhotic rats by modulating the gutlivermuscle axis

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PMID 15221859